How aging clocks can help us understand why we age—and if we can reverse it

Scientists are using aging clocks, which measure how organs age, to understand aging and potentially reverse it. These clocks, like the Horvath clock, analyze DNA methylation to estimate biological age. While these clocks have limitations in predicting individual biological age accurately, they offer insights into aging processes. Research on mice suggests that sharing blood circulation with younger individuals can rejuvenate older organisms. The pan-mammalian clock, developed by Horvath, indicates a universal aspect to aging across mammal species. Understanding when aging begins could lead to interventions to slow or reverse aging.