Technology

Researchers announce babies born from a trial of three-person IVF

Source

MIT Technology Review

Published

Jul 16, 2025

TL;DR

AI Generated

Eight babies have been born in the UK through a trial of three-person IVF, where DNA from two biological parents and a third person supplying healthy mitochondrial DNA was used. The babies were born to mothers at risk of passing on severe mitochondrial diseases, and all eight babies are reportedly healthy. The study, using mitochondrial donation technology, has been hailed as a significant achievement, although some concerns remain about health issues observed in a few babies. The Newcastle team's trial, the only one overseen by the HFEA, has been long-awaited and marks a milestone in reproductive technology advancements. Researchers are continuing to monitor the babies for any potential health implications of the procedure.

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A brief history of “three-parent babies”

Eight babies have been born in the UK using an experimental form of IVF involving DNA from three people to prevent mitochondrial diseases. This technique has been used over the past decade to help couples have children, with varying success. Some scientists criticize the term "three-parent babies," preferring "three-person IVF." While the recent UK births are seen as a success, some babies had mutated mitochondria, raising concerns about the procedure's effectiveness in preventing genetic diseases. The history of three-person IVF includes past trials, controversies, and ongoing research to improve outcomes.

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