Reformulated antibodies could be injected for easier treatment

Researchers have developed a method to reformulate therapeutic antibodies into microparticles that can be injected with a standard syringe, eliminating the need for lengthy infusions. By encapsulating antibodies into hydrogel particles using a microfluidic setup, they achieved highly concentrated solid antibodies that can be easily administered. The new formulation allows for the injection of over 700 milligrams of antibodies with a two-milliliter syringe, and the stability of the formulations was maintained for at least four months under refrigeration. Further testing in animals and scaling up the manufacturing process are the next steps for this promising development in antibody treatment.