Technology

One-shot vaccines for HIV and covid

Source

MIT Technology Review

Published

Aug 26, 2025

TL;DR

AI Generated

Researchers at MIT and the Scripps Research Institute have developed a promising single-dose vaccine approach that could protect against HIV and other diseases. By combining two different adjuvants in the vaccine, they were able to stimulate a more robust immune response in mice. The vaccine accumulated in the lymph nodes, allowing for the generation of a greater number and diversity of antibodies against the HIV protein. This strategy, which mimics natural infection processes, has the potential to create strong and broad immune responses that may only require a single vaccination, offering possibilities for new vaccine formulations for various diseases like influenza and SARS-CoV-2.

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